I have comorbid symptoms and use to take medication after college and I was not reacting really well to them. I don't know if its the same as your reactions. I went without medication (I also wasn't diagnosed until after college) until after college and after being put on them I had some terrible times reacting and adapting to them. Between that and trying to figure out how my work life was going to be, it was really difficult, plus I only made a plan to graduate college. I found that I use to eat a lot of herbs when I was younger because it was an integrated part of my culture's cuisine. I am Chinese-Vietnamese and we normally have herbs and vegetables in our dishes. I had a physically active childhood so a lot of my symptoms were under control. I played basketball, figure-skated, and played tennis competitively. My psychiatrist approaches medication from a holistic perspective first and he gave me barcopa and tulsi to drink to manage my ADHD and other symptoms, growing up I ate peppermint, basil, and other medicative plants often, so there are holistic doctors out there if you don't like the normal medication some doctors give you. I actually found that my medication made me more male brained and I struggled more with aggression on them and they made me lethargic and sleepy endlessly. I think they were inhibiting some natural chemicals that ended up being more harmful for me in the long-term if this is what you are getting at.
I also tried cannabis oil to address any inflammation issues, but I found that exercising works better for me. This might be strange to say but it might be about neuron training.